Galar Fungail 2 Publications
- Agostini, M., Cenci, E., Pericolini, E., Nocentini, G., Bistoni, G.,
Vecchiarelli, A., and Riccardi, C. (2005) The glucocorticoid-induced tumor
necrosis factor receptor-related gene modulates the response to Candida
albicans infection. Infect Immun 73: 7502-7508. [Abstract]
- Albrecht, A., Felk, A., Pichova, I., Naglik, J.R., Schaller, M., de
Groot, P., MacCallum, D., Odds, F.C., Schafer, W., Klis, F., Monod, M.
and Hube, B. (2006) Glycosylphosphatidylinositol-anchored proteases of
Candida albicans target proteins necessary for both cellular processes
and host-pathogen interactions. J Biol Chem 281: 688-694. [Abstract]
- Argimón, S., Wishart, J.A., Leng, R., Macaskill, S., Mavor, A.,
Alexandris, T., Nicholls, S., Knight, A.W., Enjalbert, B., Walmsley, R.,
Odds, F.C., Gow, N.A.R. and Brown, A.J.P. (2007) Developmental regulation
of an adhesin gene during cellular morphogenesis in the fungal pathogen
Candida albicans. Eukaryotic Cell 6, 682-692.
- Barelle, C.J., Priest, C.L., MacCallum, D.M. Gow, N.A.R., Odds, F.C.
and Brown, A.J.P. (2005) Niche-specific regulation of central metabolic
pathways in a fungal pathogen. Cell. Microbiol. 8: 961-971 [Abstract]
- Barelle, C.J., Richard, M.L., Gaillardin, C., Gow, N.A., and Brown,
A.J.P. (2006) Candida albicans VAC8 is required for vacuolar inheritance
and normal hyphal branching. Eukaryotic Cell 5: 359-367.
- Braun, B.R., van Het Hoog, M., d'Enfert, C., Martchenko, M., Dungan,
J., Kuo, A., Inglis, D.O., Uhl, M.A., Hogues, H., Berriman, M., Lorenz,
M., Levitin, A., Oberholzer, U., Bachewich, C., Harcus, D., Marcil, A.,
Dignard, D., Iouk, T., Zito, R., Frangeul, L., Tekaia, F., Rutherford,
K., Wang, E., Munro, C.A., Bates, S., Gow, N.A., Hoyer, L.L., Kohler,
G., Morschhauser, J., Newport, G., Znaidi, S., Raymond, M., Turcotte,
B., Sherlock, G., Costanzo, M., Ihmels, J., Berman, J., Sanglard, D.,
Agabian, N., Mitchell, A.P., Johnson, A.D., Whiteway, M., and Nantel,
A. (2005) A human-curated annotation of the Candida albicans genome. PLoS
Genet 1: 36-57. [Abstract]
[Free
Full Text]
- Brown, A.J.P. (2005) Integration of metabolism with virulence in Candida
albicans. In “Fungal Genomics” (Ed. Brown, A.J.P.) Mycota
XIII, Springer-Verlag, Heidelberg. pp185-203.
- Brown, A.J.P., Odds, F.C and Gow, N.A.R. (2007) Infection-related gene
expression in Candida albicans. Curr. Opin. Microbiol. 10, 307-313.
- Castillo, L., Martinez, A.I., Garcera, I., Garcia-Martinez, J., Ruiz-Herrera,
J., Valentin, E. and Sentandreu, R. (2006) Genomic Response Programs of
Candida albicans Following Protoplasting and Regeneration. Fungal Genet
Biol, 43:124-134. [Abstract]
- Castillo, L., Martínez, A.I., Gelis, S., Ruiz-Herrera, J., Valentín,
E., and Sentandreu, R. (2008) Genomic response programs of Saccharomyces
cerevisiae following protoplasting and regeneration. Fungal Genet Biol
45, 253-265.
- Copping VM, Barelle CJ, Hube B, Gow NA, Brown AJ, Odds FC. (2005) Exposure
of Candida albicans to antifungal agents affects expression of SAP2 and
SAP9 secreted proteinase genes. J Antimicrob Chemother 55, 645-54.
- Corbucci, C., Cenci, E., Skrzypek, F., Gabrielli, E., Mosci, P., Ernst,
J.F., Bistoni, F., and Vecchiarelli, A. (2007) Immune response to Candida
albicans is preserved despite defect in O mannosylation of secretory proteins
Med Mycol 18, 1-11.
- Cornet M, Bidard F, Schwarz P, Da Costa G, Blanchin-Roland S, Dromer
F, Gaillardin C. (2005) Deletions of endocytic components VPS28 and VPS32
affect growth at alkaline pH and virulence through both RIM101-dependent
and RIM101-independent pathways inCandida albicans. Infect Immun. 73:7977-87.
[Abstract]
- Cornet, M., Gaillardin, C., and Richard M.L.. (2006) Deletions of the
endocytic components VPS28 and VPS32 in Candida albicans lead to echinocandin
and azole hypersensitivity. Antimicrobial Agents and Chemotherapy 50:
3492-3495.
- d’Enfert, C. (2006) Biofilms and their role in the resistance
of pathogenic Candida to antifungal agents. Curr. Drug Targets, 7: 465-470.
[Abstract]
- d'Enfert, C., S. Goyard, S. Rodriguez-Arnaveilhe,
L. Frangeul, L. Jones, F. Tekaia, O. Bader, Antje Albrecht, L. Castillo,
A. Dominguez, J. Ernst, C. Fradin, C. Gaillardin, S. Garcia-Sanchez, P.
de Groot, B. Hube, F.M. Klis, S. Krishnamurthy, D. Kunze, M.-C. Lopez,
A. Mavor, N. Martin, I. Moszer, D. Onésime, J. Perez Martin, R.
Sentandreu, E. Valentin and A.J.P. Brown (2005) CandidaDB: a genomic database
for Candida albicans pathogenomics. Nucl. Acid Res.
33: D353-D357. [Abstract]
[Free
Full Text] [Supplementary
Material]
- d'Enfert, C., and Hube, B., eds (2007) Candida:
Comparative and functional genomics. Caister Academic Press, Norfolk,
United Kingdom.
- de Groot, P.W.J., Brandt, B.W., and Klis, F.M. (2007) Candida cell wall
proteins at the host-pathogen interface. In C. d'Enfert and B. Hube (ed.),
Candida: Comparative and functional genomics. Caister Academic Press,
Norfolk, United Kingdom
- de Groot, P.W.J., Yin, Q.Y., Weig, M., Sosinska, G.J., Klis, F.M., and
de Koster, C.G.. Mass spectrometric identification of covalently-bound
cell wall proteins from the fission yeast Schizosaccharomyces pombe. Yeast
((Epub ahead of print).
- de Groot, P.W.J., Yin, Q.Y., Weig, M., Sosinska, G.J., Klis, F.M., and
de Koster, C.G. (2007) Mass spectrometric identification of covalently
bound cell wall proteins from the fission yeast Schizosaccharomyces pombe.
Yeast 24, 267-78.
- Dennison, P.M.J., Ramsdale, M., Manson, C.L. and Brown, A.J.P. (2005)
Gene Disruption in Candida albicans using a synthetic, codon-optimised
Cre loxP system. Fungal Genetics and Biology 42: 737-748.
- Doedt, T., Krishnamurthy, S., Bockmühl, D.P., Tebarth, B., Stempel,
C., Russell, C.L., Brown, A.J.P. and Ernst, J.F. (2004) APSES proteins
regulate morphogenesis and metabolism in Candida albicans. Molec. Biol.
Cell 15, 3167-3180. [Abstract]
[Supplementary Material]
- Ellerbroek, P., Vecchiarelli, A., Hoepelman, A., and Coenjaerts, F.
(2007) Immunology of infections with Cryptococcus neoformans. In G.D.
Brown and M.G. Netea (eds.), Immunology of fungal infections. Springer,
Dordrecht, The Netherlands.
- Enjalbert, B., Smith, D.A., Cornell, M.J., Alam, I., Nicholls, S.,
Brown, A.J.P. and Quinn, J. (2006) Role of the Hog1 Stress-Activated Protein
Kinase in the Global Transcriptional Response to Stress in the Fungal
Pathogen Candida albicans. Molec Biol Cell, 17: 1018-1032.[Abstract]
[Supplementary Material]
- Enjalbert, B., MacCallum, D., Odds, F.C and Brown, A.J.P. (2007) Niche-specific
activation of the oxidative stress response by the pathogenic fungus Candida
albicans. Infect Immun 75, 2143-2151.
- Enjalbert, B., Rachini, A., Vediyappan, G., Pietrella, D., Spaccapelo,
R., Vecchiarelli, A., Brown, A.J.P., and d’Enfert, C. A synthetic,
codon-optimized Gaussia princeps luciferase gene as a new multifunctional
reporter for Candida albicans, manuscript in preparation.
- Firon, A., and d'Enfert, C. (2007) From genes to function: systematic
approaches used to study Candida albicans and Candida glabrata biology
and pathogenesis, p. 51-70. In C. d'Enfert and B. Hube (ed.), Candida:
Comparative and functional genomics. Caister Academic Press, Norfolk,
United Kingdom.
- Firon, A., Aubert, S., Iraqui, I., Guadagnini, S., Goyard, S., Prevost,
M.C., Janbon, G., and d'Enfert, C. (2007). The SUN41 and SUN42 genes are
essential for cell separation in Candida albicans. Mol Microbiol 66, 1256-1275.
- Fradin, C., De Groot, P., MacCallum, D., Klis, F., Odds, F.C., and
Hube, B. (2005). Granulocytes govern the transcriptional response, morphology
and proliferation of Candida albicans in human blood. Mol Microbiol, 56:397-415.
[Abstract]
[Supplementary Material]
- Fradin, C., Thewes, S., Zakikhany, K., Albrecht, A., Bader, O., Kunze,
D., and Hube, B. (2004) Transcriptional profiling of Candida albicans
during infections. Mikologia Lekarska 11: 157-163.
- Fradin, C., and Hube, B. (2005). Transcriptional profiling of Candida
albicans in human blood. Microbe 1:76-80.
- Fradin, C., Mavor, A. L., Weindl, G., Schaller, M., Hanke, K., Kaufmann,
S. H., Mollenkopf, H., and Hube, B. (2007) The early transcriptional response
of human granulocytes to infection with Candida albicans is not essential
for killing but reflects cellular communications. Infect Immun 75, 1493-1501.
- Garcerá, A., Castillo, L., Martínez, A.I., Elorza, M.V.,
Valentín, E. and Sentandreu. R. (2005) Anchorage of Candida albicans
Ssr1 in the cell wall and transcript profiling of the null mutant. Res
Microbiol 156: 911-20. [Abstract]
- Garcia-Sanchez, S., Mavor, A.L., Russell, C.L., Argimon, S., Dennison,
P., Enjalbert, B., and Brown, A.J. (2005) Global roles of Ssn6 in Tup1-
and Nrg1-dependent gene regulation in the fungal pathogen, Candida albicans.
Mol Biol Cell 16: 2913-2925. [Abstract]
[Supplementary Material]
- Goyard, S., Knechtle, P., Chauvel, M., Mallet, A., Prévost, M.-C.,
Proux, C., Coppée, J.-Y., Schwartz, P., Dromer, F., Park, H., Filler,
S.G., Janbon, G. and d'Enfert, C. (2008) The Yak1 kinase is involved in
the initiation and maintenance of hyphal growth in Candida albicans. Mol
Biol Cell, 19:2251-2266.
- Hube, B. (2004) From commensal to pathogen: stage and tissue specific
gene expression of Candida albicans. Current Opinion in Microbiology 7:1-6.
[Abstract]
- Hube, B. (2006) Infection-associated genes of Candida albicans. Fut
Microbiol 1, 209-218.
- Kaplanek, P., de Boer, A., Gross, U., de Groot, P., Hube, B., and Weig,
M. (2006). Candida and Candidosis Today: where are we, and where to go?
Meeting report on the Interdisciplinary Forum on Candidosis (IFOCAN),
Goettingen, Germany, 23/09–25/09/2005. FEMS-Yeast Research 6: 1290-1294.
- Klis F.M., Sosinska G., de Groot P., Brul S., Hellingwerf K., de Koster
C. (2005) Cell wall dynamics in Saccharomyces cerevisiae and Candida albicans.
Mycoses 48 (Suppl) : 21-22.
- Knechtle, P., Goyard, S., Brachat, S., Ibrahim-Granet, O., and d'Enfert,
C. (2005) Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3
of Candida albicans are dispensable for morphogenesis and host-pathogen
interaction. Res Microbiol 156: 822-829. [Abstract]
- Martinez, A.I., Castillo, L., Garcera, A., Valentin, V. and Sentandreu,
R. (2004). Role of pir1 in the construction of Candida albicans cell wall.
Microbiology 150, 3151-3161. [Abstract]
- Mavor, A., Thewes, S., and Hube, B. (2005). Systemic fungal infections
caused by Candida species: Epidemiology, infection process and virulence
factors. The Journal of Current Drug Targets 6: 863-874. [Abstract]
- Monari, C., Bistoni, F., Casadevall, A., Pericolini, E., Pietrella,
D., Kozel, T.R., and Vecchiarelli, A. (2005) Glucuronoxylomannan, a microbial
compound, regulates expression of costimulatory molecules and production
of cytokines in macrophages. J Infect Dis. 191,127-137.[Abstract]
- Monari, C., Pericolini, E., Bistoni, G., Casadevall, A., Kozel, T.R.,
and Vecchiarelli, A. (2005) Cryptococcus neoformans capsular glucuronoxylomannan
induces expression of FasLigand in macrophages Journal Immunol, 174: 3461-3468.
[Abstract]
- Moreno-Ruiz, E., Ortu, G., de Groot, P., Cottier, F., Klis, F., Goyard,
S., and d’Enfert, C. The Pga59 and Pga62 GPI-anchored proteins are
required for cell wall integrity in Candida albicans, manuscript in preparation.
- Munro, C., Fradin, C., Bader, O. and Hube, B. (2006). Postgenomic approaches
to analyse Candida albicans pathogenesis. The Mycota. A. Brown. Berlin,
Springer-Verlag. XIII: Fungal Genomics: 163-184.
- Netea, M.G., Gow, N.A.R., Munro, C.A., Bates, S., Collins, C., Ferwerda,
G., Hobson, R.P., Bertram, G., Hughes, H.B., Jansen, T., Jacobs, L., Buurman,
E.T., Gijzen, K., Williams, D.L., Torensma, R., McKinnon, A., MacCallum,
D.M., Odds, F.C., Van der Meer, J.W.M., Brown, A.J.P. and Kullberg, B.J.
(2006) Immune sensing of Candida albicans: cooperative recognition of
mannans and glucan by lectin and Toll-like receptors. Journalof Clinical
Investigation 116: 1642-1650.
- Nicholls, S., Straffon, M., Enjalbert, B., Nantel, A., Macaskill, S.,
Whiteway, M. and Brown, A.J.P. (2004) Msn2/4-like transcription factors
play no obvious roles in the stress responses of the fungal pathogen,
Candida albicans. Eukaryotic Cell, 3: 1111-1123. [Abstract]
- Pedreño, Y., Maicas, S., Argüelles, J-C., Sentandreu, R.
and Valentin, E. (2004). The atc1 gene encodes a cell wall-linked acid
trehalase required for growth on trehalose in Candida albicans. J. Biol.
Chem. 279, 40852-40860. [Abstract]
- Peltroche-Llacsahuanga, H., Goyard, S., d'Enfert, C., Prill, S.K., Ernst,
J.F. (2006) Protein O-mannosyltransferase isoforms regulate biofilm formation
in Candida albicans. Antimicrobial Agents and Chemotherapy. 50: 3488-3491.
- Pietrella, D., Bistoni,G., Corbucci,C., Perito ,S., and Vecchiarelli,
A. (2006). Candida albicans mannoprotein influences the biological functions
of dendritic cells. Cell Microbiol, 8 : 602-612. [Abstract]
- Pietrella, D., C. Corbucci, S. Perito, G. Bistoni, and Vecchiarelli
A. (2005) Mannoproteins from Cryptococcus neoformans promote dendritic
cell maturation and activation. Infect. Immun. 73, 820-827. [Abstract]
- Pietrella, D., Lupo, P., Bistoni, F., and Vecchiarelli, A. (2004) An
early imbalance of interleukin 12 influences the adjuvant effect of mannoproteins
of Cryptococcus neoformans. Cell Microbiol. 6, 6883-6891. [Abstract]
- Plaine, A., Walker, L., da Costa, G., McKinnon, A., Gow, N.A.R., Gaillardin,
C., Munro, C.A., and Richard, M.L. Functional analysis of Candida albicans
GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity,
under revision.
- Quinn, J. and Brown, A.J.P. (2007) Stress Responses in Candida albicans.
In C. d'Enfert and B. Hube (ed.), Candida: Comparative and functional
genomics. Caister Academic Press, Norfolk, United Kingdom.
- Rachini, A., Pietrella, D., Lupo, P., Torosantucci, A., Chiani, P.,
Bromuro, C., Proietti, C., Bistoni, F., Cassone, A., and Vecchiarelli,
A. (2007) An anti-beta-glucan monoclonal antibody inhibits growth and
capsule formation of Cryptococcus neoformans in vitro and exerts therapeutic,
anticryptococcal activity in vivo. Infect Immun 11, 5085-5094.
- Román, E., Cottier, F., Ernst, J. F. and Pla, J. (2007) Msb2
is an upstream sensor of the Cek1-mediated signaling pathway in Candida
albicans. Submitted.
- Rossignol, T., Lechat, P., Cuomo, C., Zeng, Q., Moszer, I., and d'Enfert,
C. (2007) CandidaDB: a multi-genome database for Candida species and related
Saccharomycotina. Nucleic Acids Res 36, D557-561.
- Rouabhia, M. Schaller, M., Vecchiarelli, A. Prill, S.K.H. Giasson,
L. and Ernst, J.F. (2005) Virulence of the fungal pathogen of Candida
albicans requires the five isoforms of protein mannosyltransferases. Infect
Immun 73: 4571-4580. [Abstract]
- Ruiz-Herrera, J. Elorza, M.V., Alvarez, P.E. and Sentandreu, R. (2004).
Biosynthesis of the fungal cell wall. In: Pathogenic Fungi: Pathogenic
fungi: structural biology and taxonomy. Edited by: G. San-Blas and R.
Calderone. Caister Academic Press, Wymondham, Norfolk, UK, p. 41-99.
- Ruiz-Herrera, J., Elorza, M.V., Valentín, E. and Sentandreu,
R. 2006. Molecular organization of Candida albicans cell wall and its
relation to pathogenicity. FEMS Yeast Reseach 6: 14-29.
- Schaller, M., Korting, H., Borelli, C., Hamm, G. and Hube, B. (2005)
Candida albicans-Secreted Aspartic Proteinases Modify the Epithelial Cytokine
Response in an In Vitro Model of Vaginal Candidiasis. Infect Immun 73:
2758-2765 [Abstract]
- Schaller, M. and Hube, B. (2004) Candida albicans-Infektionsmodelle.
Bioforum 11/2004: 2-3.
- Schaller, M., Boeld, U., Oberbauer, S., Hamm, G., Hube, B., and Korting,
H.C. (2004) Polymorphonuclear leukocytes (PMNs) induce protective Th1-type
cytokine epithelial responses in an in vitro model of oral candidosis..
Microbiology 150: 2807-2813. [Abstract]
- Schaller, M., Zakikhany, K., Naglik, J. R., Weindl, G., and Hube, B.
(2006) Models of oral and vaginal candidiasis based on in vitro reconstituted
human epithelia. Nature Protocols 1, 2767-2773.
- Schmidt, P., Walker, J., Selway, L., Stead, D., Yin, Z., Enjalbert,
B., Weig, M. and Brown, A.J.P. (2008) Proteomic analysis of the pH response
in the fungal pathogen Candida glabrata. Proteomics (In press).
- Sentandreu, R., Elorza, M.V., Valentín, V. and Ruiz-Herrera,
J. (2004). The Structure and Composition of the Fungal Cell Wall. In:
Pathogenic fungi: structural biology and taxonomy. In: Pathogenic Fungi:
Pathogenic fungi: structural biology and taxonomy. Edited by: G. San-Blas
and R. Calderone. Caister Academic Press, Wymondham, Norfolk, UK, p. 3-39.
- Setiadi, E. R., Doedt, T., Cottier, F., Noffz, C. and Ernst, J. F. (2006)
Transcriptional response of Candida albicans to hypoxia: linkage of oxygen-sensing-
and Efg1p-regulatory networks. Journal of Molecular Biology 361: 399-411.
- Soloviev, D.A. Fonzi, W.A., Sentandreu, R., Pluskota, E., Forsyth, C.B.,
Yadav, S. and Edward F. Plow, E.F. 2007. Identification of Pra1 released
from Candida albicans as the major ligand for leukocyte Integrin ?M?2.
J. Immunology. (in press).
- Sosinska, G.J., de Groot, P.W.J., Dekker, H.L., de Koster, C.G., Hellingwerf
K.J., and Klis, F.M. Biomats of Candida albicans growing on semi-solid
mucin-containing agarose. Manuscript in preparation.
- Sosinska, G.J., de Groot, P.W.J., Teixeira de Mattos, M.J., Dekker,
H.L., de Koster, C.G., Hellingwerf, K.J., and Klis, F.M. (2008) Hypoxic
conditions and iron restriction affect the cell-wall proteome of Candida
albicans grown under vagina-simulative conditions Microbiology 154, 510-520.
- Thewes, S., Reed, H. K., Grosse-Siestrup, C., Groneberg, D. A., Meissler,
M., Schaller, M., and Hube, B. (2007). Haemoperfused liver as an ex vivo
model for organ invasion of Candida albicans. J Med Microbiol 56, 266-270.
- Tournu, H., Tripathi, G., Bertram, G., Macaskill, S., Mavor, A., Walker,
L., Odds, F.C., Gow, N.A., and Brown, A.J. (2005) Global role of the protein
kinase Gcn2 in the human pathogen Candida albicans. Eukaryot Cell 4: 1687-1696.
[Abstract]
- Veses, V., Casanova, M., Murgui, A., Dominguez, A., Gow, N.A., and
Martinez, J.P. (2005) ABG1, a novel and essential Candida albicans gene
encoding a vacuolar protein involved in cytokinesis and hyphal branching.
Eukaryot Cell 4: 1088-1101. [Abstract]
- Weyler, M., Bidard-Michelot, F., Gaillardin, C., and Richard, M.L. Early
transcriptional events triggered by Rim101 in C. albicans. Under revision.
- Wimalasena, T.T., Enjalbert, B., Guillemette, T., Plumridge, A., Budge,
S., Brown, A.J.P. and Archer, D.B (2008) Impact of the unfolded protein
response upon the genome-wide expression patterns and polarized growth
of Candida albicans. Fungal Gen Biol under revision.
- Wozniok, I., Hornbach, A., Schmitt, C., Frosch, M., Einsele, H., Hube,
B., Löffler, J., and Kurzai, O. (2008) Induction of ERK-kinase signalling
triggers morphotype-specific killing of Candida albicans filaments by
human neutrophils. Cell Microbiol 10, 807-820.
- Yin, Q.Y., de Groot, P.W., de Koster, C.G., and Klis, F.M. (2008) Mass
spectrometry-based proteomics of fungal wall glycoproteins. Trends Microbiol
16, 20-26.
- Zakikhany, K., Naglik, J. R., Schmidt-Westhausen, A., Holland, G., Schaller, M., and Hube, B. (2007) In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol 9, 2938-54.
